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br In vivo visualization of aromatase with positron emission
2024-01-15

In vivo visualization of aromatase with positron emission tomography (PET) Positron emission tomography (PET) utilizes the high Puromycin photons formed during the annihilation of positrons to detect the changes in the amount and localization of injected radiopharmaceuticals in the living body (r
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Based on the results of studies done to date
2024-01-15

Based on the results of studies done to-date, there are three characteristics that make a letrozole-based protocol attractive for use in cattle: 1) it is steroid-free, 2) it is cost-effective and requires a shorter time and fewer animal handlings than conventional methods (Table 1), and 3) it may ha
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br Conclusion br Conflicts of interest br Acknowledgements T
2024-01-15

Conclusion Conflicts of interest Acknowledgements The authors are grateful to the Ministry of Food Processing Industries, Govt of India (V45/MFPI/R&D/2000 Vol.IV) and Department of Biotechnology, New Delhi, Govt. of India (BT/475/NE/TBP/20132), American Bamboo Society and Ned Jaquith Founda
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Use of RASB is associated with potential concerns
2024-01-15

Use of RASB is associated with potential concerns about side effects such as acute kidney injury or hyperkalemia, and clinicians are reluctant to prescribe RASB in patients with severe renal dysfunction (estimated GFR Conclusions Conflict of interest Acknowledgement Introduction Renin-an
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br Materials and met http
2024-01-13

Materials and methods Results The values for body weight are shown in Fig. 1. Body weight was measured every day. The body weight of the young mice in the control (i.e. no-stress) group was not significantly different from that of the young mice in the stress group. However, the middle-aged mi
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br Methods br Results br Discussion
2024-01-13

Methods Results Discussion By following a large cohort of older persons for up to 11 years, we found that subjects with more degraded FR in motor activity (i.e., weaker temporal activity correlations at time scales calcifediol receptor pathologies affect diverse clinical phenotypes and are
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br Methods br Results br
2024-01-13

Methods Results Discussion Chronic stress renders individuals vulnerable to diseases, and this effect might be, at least partially, mediated by stress hormone-induced immunosuppression. Therefore, investigating the effects of catecholamines on immune hsp70 inhibitor is of high relevance. W
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Previous studies suggest that TGF contributes to the
2024-01-13

Previous studies suggest that TGF-β contributes to the pathogenesis of diabetic renal injury [47]. TGF-β stimulates matrix production and prevents matrix degradation, which leads to increase collagen deposition and glomerulosclerosis [48]. In the current study ABT702 significantly reduced renal coll
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br Materials and methods br
2024-01-13

Materials and methods Results and discussion Conclusion Amino-functionalized mesoporous TiO2-NH2 microparticles were used to immobilize ADA, followed by GLU cross-linking. The mesopores provided a natural microenvironment with sufficient room for the enzyme to efficiently perform its cataly
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The structures of these compounds were confirmed from
2024-01-13

The structures of these compounds were confirmed from their spectral and micro analytical data. Based on [M + H] 367, molecular formula of was established as CHON. The IR spectrum of showed cox 2 inhibitor due to CO stretching at 1700 Cm & OH stretching at 3188 Cm indicating that compound contains o
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For both the hydroxylation and lyase reactions the heme
2024-01-13

For both, the 17α-hydroxylation and 17, 20-lyase reactions, the heme iron center of P450 17A1 receives electron reducing equivalents from CPR. Both reactions require one pair of electrons and molecular oxygen for the conversion of the substrate into product in each catalytic cycle. However, the 17,2
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Aromatization of the pyrrole ring after anion capturing usin
2024-01-13

Aromatization of the pyrrole ring after anion capturing, using acceptor atoms with electron deficiency (B & Be), and substitution of strong electron withdrawing groups such as CN were three strategies used to design a new class of anion receptors. Comparison of the anion affinities of these anion re
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br Declaration of interest br Funding br
2024-01-13

Declaration of interest Funding Introduction The endocrine disruptor bisphenol A (BPA) is a high-production chemical used in several consumer products, including polycarbonate bottles, epoxy resins, dental sealants, and thermal paper receipts (Geens et al., 2012). Importantly, BPA monomers
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NO is an important mediator for
2024-01-13

NO is an important mediator for maintaining bone integrity since it plays a role in the bone remodeling process. It was shown that mechanical strain and shear stress induce NO synthesis in osteoblasts and osteocytes (van't Hof & Stuart, 2001). It was reported that mechanical loading influences its a
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br STAR Methods br Author Contributions br Acknowledgments W
2024-01-12

STAR★Methods Author Contributions Acknowledgments We thank Craig D. Wenger and Neva C. Durand for helpful advice, guidance, and discussions. D.H.P. is supported by the NIH National Human Genome Research Institute (NHGRI) (grant R00HG008662) and the Damon Runyon Cancer Research Foundation (D
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