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Ajzenman et al reported improved
2022-08-12

Ajzenman et al reported improved stability and postural parameters in ASD children after EAT. Other authors presented similar findings,61, 62, 63, 64 although the studies were conducted among children with CP, and reported improved muscle symmetry,, stability of the head and the trunk, motor functio
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Finally it is possible that the increase in the number
2022-08-12

Finally, it is possible that the increase in the number of EAAT-3-labelled cells in the DG at PD 60, when compared with the control and experimental animals at PD 14, is associated with natural changes in the number of neurons present during the postnatal development of the hippocampus (41, 42) and,
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GPR can signal through not only
2022-08-12

GPR40 can signal through not only IP3 but also cAMP depending upon the type of agonist ligand used. A full agonist engages both signaling mechanisms in contrast to the endogenous long-chain fatty LCL161 (LCFA) ligands and partial agonists. Thus, stimulation of GPR40 by endogenous LCFAs or by the sy
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Beside these studies related to food
2022-08-12

Beside these studies related to food, several groups examined the role of ghrelin in the actions of psychostimulants. Modulation of the ghrelin system and food restriction alter locomotor sensitization, DA release in the NAc, and CPP induced by cocaine, amphetamine, and nicotine (Abizaid et al., 201
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Emergent studies have recently shown that Sherpas living
2022-08-12

Emergent studies have recently shown that Sherpas living at high altitude have adaptations that make life at high altitude more compatible. Sherpas are known to have blood Hb concentrations about the same as lowlanders and Han populations [30]. This is different from what happens to lowlanders, Han
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The most ubiquitous serine threonine phosphatases such as
2022-08-12

The most ubiquitous serine/threonine phosphatases, such as PP1, PP2A, and PP2B are known to contribute to the majority of phosphatase activity in the heart [4]. Dysregulation of these and other PPs have been found in numerous CVDs, including heart failure (HF), and may play a critical role in reduce
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The multiple sequence analysis showed that
2022-08-11

The multiple sequence analysis showed that the putative amino aa-utp receptor sequence of HbFDP had 80–99% identity to the FDPs from H. brasiliensis, Lupinus and T. wilfordii, Malus×domestica, Centella asiatica, M. sativa, M.recutita, accession H. annuus, and A. thaliana. The present results are in
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donepezil hydrochloride mg TLRs were originally identified a
2022-08-11

TLRs were originally identified as pathogen-associated molecular pattern recognition receptors that recognized exogenous ligands in response to infection [31]. In cirrhotic mice or patients, the gastrointestinal tract produces and absorbs considerable bacterial LPS with increased permeability of the
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The rationale for developing HDACi
2022-08-11

The rationale for developing HDACi as anticancer agents was based on their ability to induce the hyperacetylation of histones and nonhistone proteins, resulting in increased differentiation, apoptosis, and Chloramphenicol arrest of cancer cells 1, 2, 3. HDACi have been used in the treatment of hema
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br Discussion Regulation of redox homeostasis is critical in
2022-08-11

Discussion Regulation of redox homeostasis is critical in the maintenance of normal cell functions, and both glutathione S-transferase and peroxiredoxin enzymes are important contributors to this process. There are numerous reports of aberrant expression patterns of GSTP linked with cancer and wi
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br Author contributions Animal experiments real
2022-08-11

Author contributions Animal experiments, real time PCR and western blots were performed at the Department of Physiology, CIMUS, University of Santiago de Compostela and Department of Cell Biology, Physiology and Immunology, Instituto Maimónides de Investigaciones Biomédicas (IMIBIC) / Reina Sofia
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br Mechanism of action of herbs and their active
2022-08-11

Mechanism of action of herbs and their active constituents used in hair loss treatment The hair growth cycle consists of 4 stages known as the anagen (active growth phase; takes 2–7years), catagen (involuting or regressing phase; takes approx. 2weeks), telogen (short resting phase; takes approx.
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To further explain the energy differences between Group A
2022-08-11

. To further explain the energy differences between Group-A and Group-B, the average distances between ligands and the zinc cation were obtained from the last 1ns trajectory. It turns out that the members of group A were within the coordination distance of the zinc ion, whereas those of group B stay
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The following are the supplementary data related
2022-08-11

The following are the supplementary data related to this article. Author contribution Conflict of interest Introduction Thrombosis (arterial and venous) is a major cause of vascular obstructive diseases including myocardial infarction, cerebral infarction and pulmonary embolism. Glycoprote
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Growing evidence suggests that the glycine site seems to
2022-08-11

Growing evidence suggests that the glycine site seems to play a pivotal role in NMDAR-related function. For example, it daunorubicin has been demonstrated in a hippocampal slice study that the glycine site sub-serves the spatiotemporal detection of synaptic activity (Li et al., 2009). Moreover, mice
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