• TTNPB In this study we examined whether zebrafish ionocytes

  2022-03-22

  

  In this study, we examined whether zebrafish ionocytes might also share other types of similarity in transport function with kidney cells. In addition to ion transport, mammalian kidney TTNPB also play key roles in xenobiotic elimination, through the action of ATP-Binding Cassette (ABC) transporter

• br Materials and methods br Results br Discussion

  2022-03-22

  

  Materials and methods Results Discussion In this study, we demonstrated, for the first time, that manipulation of AKR1D1 expression and activity is able to regulate glucocorticoid availability in liver and non-liver cell lines. AKR1D1 over-expression leads to increased glucocorticoid cleara

• In patients with type diabetes

  2022-03-22

  

  In patients with type 2 diabetes glucagon receptor antagonism led lowered fasting glucose however not postprandial glucose levels [9], which may reflect that glucagon may not be of particular importance for the diabetic hyperglycemia upon a meal. Current glucagon receptor antagonists have however be

• Sexual size dimorphism has been observed in European eel and

  2022-03-22

  

  Sexual size dimorphism has been observed in European eel and half-smooth tongue sole (Cynoglossus semilaevis), as females have a faster growth rate than males, (Degani, G., et al., 2003, Ma, Q., et al., 2012). Ma et al. 2011 reported that the mRNA level of GH was higher in the pituitary gland of bot

• Analgesic activity was evaluated by measuring tail flick lat

  2022-03-22

  

  Analgesic activity was evaluated by measuring tail flick latencies to the immersion of rat’s tail in water, maintained at ∼51°C [18] after recovery from anesthesia. Typically, rats were immobilized inside a restrainer, leaving only the tail exposed, which was then immersed into the hot water bath, a

• EZLink Sulfo-NHS-SS-Biotin Kit receptor br Introduction It i

  2022-03-22

  

  Introduction It is well known that conventional cancer treatment strategies, such as surgery, radiotherapy, and chemotherapy all have their own limitations, which lead to an unsatisfactory therapeutic effect. Under this situation, the combination of two or more therapeutic strategies has recently

• The glycolytic activator phosphofructo kinase fructose

  2022-03-22

  

  The glycolytic activator 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase 3 (PFKFB3) is well-known as a downstream substrate of hypoxia-inducible factor 1α (HIF-1α) signaling pathway [5,6]. Tumor hypoxia has long been associated with increased malignancy, poor prognosis and drug resistance. HIF-

• Now recall that a cozero element of a frame

  2022-03-21

  

  Now recall that a cozero Peficitinb of a frame L is an element of the form for some continuous real-valued function h in L. Equivalently, is a cozero element if and only if there exists an such that and . This is the pointfree counterpart to the notion of a cozero set for ordinary continuous real-va

• Apo E is defined as a polym http www

  2022-03-21

  

  Apo E is defined as a polymorphic protein arising from three alleles. The human Apo E gene was widely studied and described to be located on chromosome 19, closely linked to the Apo C-I/C-II gene complex [9]. The three major alleles, termed Epsilon-2, Epsilon-3 and Epsilon-4 have been reported [10].

• Our data indicate that curcumin reduced MDA and

  2022-03-21

  

  Our data indicate that curcumin reduced MDA and LOOH formation in plasma and kidney induced by gentamicin treatment. The results demonstrate the protective effect of this compound against oxidative damage to these membranes. Moreover, the ability of curcumin to reduce the formation of LOOH induced b

• Recently it was found that hypoxia results in the phosphoryl

  2022-03-21

  

  Recently, it was found that hypoxia results in the phosphorylation of β-catenin at Y654 in a Src-dependent manner (Xi et al., 2013). All β-catenin phosphorylated at this residue was found complexed with Hif1α and it was demonstrated that this β-catenin phosphorylation was required for Src to promot

• sirtuin Our results show that deletion of

  2022-03-21

  

  Our results show that deletion of the first loop of Obg does not abolish the augmentation of the GTPase activity of CgtAvc, revealing that the first loop is mainly responsible for the anchoring of the protein in the 50S and the transient interaction with ribosome is enough for augmentation of GTPase

• Indeed GSTP mRNA appears to be already highly stable

  2022-03-21

  

  Indeed GSTP1-1 mRNA appears to be already highly stable in K562 leukemia CCT245737 synthesis with a half-live of more then 40h which is even further increasing to 92h after hemin treatment and erythroid differentiation. Previous reports quantified GST mRNA half-lives which depend on the cellular mod

• It was reported that GPR is

  2022-03-21

  

  It was reported that GPR120 is expressed on macrophages in adipose tissue (Oh et al., 2010). Whether GPR120-positive Bleomycin A5 hydrochloride synthesis in human and rat pancreas belongs to macrophages was studied. CD68 is a transmembrane glycoprotein that is highly expressed by human monocytes and

• Mapping and separation of the anti GlyT C epitopes allowed

  2022-03-21

  

  Mapping and separation of the anti-GlyT1C epitopes allowed us to verify the existence of calpain cleavage sites in isolated mouse synaptosomes. In order to allow calcium to enter the intrasynaptosomal compartment and activate endogenous calpain, we incubated synaptosomes in hypoosmotic high (200μM)

15498 records 455/1034 page Previous Next First page 上5页 451452453454455 下5页 Last page